SurePrep — Automated NGS Library Preparation

One chip. One connected run. A complete library.

SurePrep automates the entire NGS library preparation workflow on a single digital microfluidics chip. From fragmentation and end-repair through adapter ligation, PCR and purification, the complete workflow runs on-chip with minimal hands-on intervention.

Precise, oil-enclosed droplets enable small reaction volumes, reducing reagent consumption, manual handling and the risk of cross-contamination. The result is a streamlined, reproducible library preparation workflow designed to help laboratories process samples efficiently and with confidence.

SurePrep instrument with chip loaded
SurePrep instrument, loaded with a library preparation chip.
SurePrep touchscreen interface showing digital microfluidics for library preparation
Touchscreen interface for method selection and run monitoring.
Why SurePrep?

Built for reproducible, hands-off library prep

  • Fully automated workflow — five library preparation steps in one uninterrupted on-chip run.
  • Parallel processing — processes 1–4 samples simultaneously.
  • Reduced reagent use — small reaction volumes help minimise reagent consumption.
  • Less hands-on time — load a method, start the run and let the instrument work autonomously.
  • Flexible workflow support — compatible with a range of validated reagent kits.
One platform, two chip configurations

Match the workflow to your sequencing application

SurePrep uses the same instrument and software platform with two chip formats, allowing the workflow to be matched to your sequencing application.

LibPrep chip for whole-genome sequencing

LibPrep Chip — Whole-Genome Sequencing

The LibPrep chip is designed for whole-genome sequencing workflows, automating the complete WGS library preparation process from DNA fragmentation through to final purification.

Validated reagent kits

NEBRoche / KAPAVazymeNanodigimbioYeasen
SurePrep chip for exome and targeted NGS

SurePrep Chip — Exome & Targeted NGS

The SurePrep chip is configured for whole-exome sequencing and targeted NGS applications, supporting selected hybrid-capture and tumour-screen workflows.

Validated reagent kits

Roche NimbleGenAgilent SureSelectAmoyDxBurning RockRightongene

Applications include HIV, COVID and Flu A–B workflows.

See SurePrep in your lab

Request the brochure or speak with our team about integrating SurePrep into your sequencing workflow.